tour metrics' potent products equipment and containment technology.
In early 2009, Metrics completed our new dedicated Potent Products cGMP Facility. This facility is now fully operational and can accommodate Phase I through III projects up to 10 kilograms in size. This dedicated facility provides total engineered containment of processes with hard-wall isolation technologies. Containment is achieved at levels approximately 30 nanograms per cubic meter of room air.
Join us as we take a closer look at our new potent facility – and the safety and security it offers your projects.
Here's how it works:
Transcript:
Potent Capabilities.
Custom Engineered for Success.
Two processing rooms are designed for the one-way flow of materials, personnel and equipment. They come complete with independent entry double airlocks, independent decontamination showers and exit airlocks, independent equipment airlocks, and access to a dedicated washroom.
But what really makes our potent facility unique is the integration of standard equipment into a customizable isolation system.
First, we’ve engineered a series of multi-use, hard-wall isolators that can accommodate up to three individual pieces of processing equipment—with a total of 8 individual equipment bays available throughout the suite. And although the processing equipment itself is familiar, we’ve modified each by installing it through a metal baffle, which fits into any bay on any isolator. These baffles form the rear wall of the isolator.
So now, Metrics can accommodate a wide range of simple or complex pharmaceutical processes.
Once required equipment is in place, the isolators are sealed and pressurized. Negative pressure at 0.3 inches of water imparts additional protection. Each isolator contains all required utility connections.
All clean equipment is housed in the equipment storage room. We’ve also designed a customized storage system, making it easy to move needed processing equipment through the equipment airlocks and into the processing rooms.
In addition, to our multi-use isolators that accommodate many unit operations , we’ve also worked with leading equipment manufacturers to design an isolated fluid bed dryer and an integrated tablet press.
Finally, our standardized 270 millimeter Rapid Transfer Port allows us to transfer product from isolator to isolator, or safely export the final product and waste from inside the potent facility.
To learn more about Metrics and our dedicated potent facility, speak with one of our representatives and veteran scientists. We’ll be glad to tell you more.
